Scientific publications list – Onasis

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PUBLICATIONS

Impactful Publications

For the past 10 years, the Buganim Lab has been dedicated to studying and investigating the process of epigenetic reprogramming. Our research has led to the identification of multiple gene combinations that can reshape the epigenetic landscape of cells, converting them into embryonic and placental stem cells. In addition to developing our own technology for this epigenetic reshaping, we also focus extensively on understanding the underlying mechanisms that enable this process. Below is a selected list of publications that highlight our work in epigenetic reprogramming.

Unlocking trophectoderm mysteries: In vivo and in vitro perspectives on human and mouse trophoblast fate induction

Complex Haploinsufficiency in Pluripotent Cells Yields Somatic Cells with DNA Methylation Abnormalities and Pluripotency Induction Defects

Pluripotency-independent Induction of Trophoblast Stem Cells from Human Fibroblasts

Comparative Parallel Multi-Omics Analysis of Cell Undergoing Reprogramming to Pluripotent and Trophectoderm States

Direct Induction of the Three Pre-Implantation Blastocyst Cell Types from Fibroblasts

Back to Basics: Refined Nuclear Reprogramming Techniques Yield Higher-Quality Stem Cells

Nuclear Reprogramming by Defined Factors: Quantity vs Quality

Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells

The Developmental Potential of iPSCs is Greatly Influenced by Reprogramming Factor Selection

Mechanisms and Models of Somatic Cell Reprogramming

Single-cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

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